Related Experiment Video
Updated: Nov 16, 2025
08:31
A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
4.1K
Recurrent pericarditis: an update on diagnosis and management
Alessandro Andreis1, Massimo Imazio2, Matteo Casula1
1Division of Cardiology, Department of Medical Sciences, Città Della Salute E Della Scienza Di Torino Hospital, University of Torino, Corso Bramante 88, 10141, Torino, Italy.
Internal and Emergency Medicine
|February 28, 2021
Summary
Recurrent pericarditis poses a clinical challenge, especially with treatment resistance. This review covers diagnosis and novel therapies, including anti-interleukin-1 agents for refractory cases.
Area of Science:
- Cardiology
- Immunology
- Inflammatory Diseases
Background:
- Recurrent pericarditis presents significant clinical challenges, particularly in patients unresponsive or intolerant to standard treatments.
- Accurate diagnosis, potentially aided by advanced imaging, is crucial for effective symptom management and preventing future episodes.
- Emerging research into cardiovascular inflammatory pathways has prompted investigation into targeted therapies.
Purpose of the Study:
- To review the diagnostic approaches for recurrent pericarditis.
- To discuss the latest therapeutic advancements for recurrent pericarditis.
- To highlight the role of anti-interleukin-1 agents in managing refractory cases.
Main Methods:
- Comprehensive literature search of major bibliographic databases (MEDLINE/PubMed, Scopus, EMBASE, etc.).
- Keywords used included "recurrent pericarditis", "diagnosis", "treatment", "IL-1", and "inflammation".
- Focus on diagnostic assessment and modern therapeutic strategies.
Main Results:
- The review synthesizes current knowledge on diagnosing recurrent pericarditis.
- It explores recent therapeutic advances, including the use of anti-interleukin-1 agents.
- Evidence suggests these targeted therapies are promising for difficult-to-treat patients.
Conclusions:
- Accurate diagnosis is paramount for managing recurrent pericarditis.
- Anti-interleukin-1 agents represent a significant advancement in treating refractory recurrent pericarditis.
- Further research and clinical application of targeted therapies are warranted.
Related Concept Videos
01:17Pericarditis III: Medical Management
104
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
104
01:19Pericarditis II: Clinical Features and Diagnostic Tests
141
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
141
01:25Pericarditis IV: Nursing Management
155
Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
155
01:22Pericarditis I: Introduction
113
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
113
01:18Endocarditis III: Medical Management
89
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
89
01:22Myocarditis IV: Nursing Management
99
Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
99