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Related Concept Videos

Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

958
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
958
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

3.6K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
3.6K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.8K
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.0K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.0K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

1.5K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Human Genetics01:28

Human Genetics

1.1K
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
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Related Experiment Video

Updated: Nov 16, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
05:53

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

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Advances in asthma genetics.

Mayank Bansal1, Mayank Garg1, Anurag Agrawal1

  • 1CSIR-Institute of Genomics and Integrative Biology, Delhi, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.

Advances in Genetics
|March 1, 2021
PubMed
Summary
This summary is machine-generated.

Predicting asthma risk is challenging due to genetic factors. Current genomic approaches have limitations, hindering a full understanding of asthma

Keywords:
Airway diseaseAsthmaGeneticsGenomicsMicrobiome

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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Related Experiment Videos

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Area of Science:

  • Genetics and genomics
  • Respiratory medicine
  • Disease risk prediction

Background:

  • Asthma exhibits a significant genetic component.
  • Over 100 genetic associations for asthma have been identified.
  • Current methods struggle to systematically predict asthma risk.

Purpose of the Study:

  • To address the gap in understanding and predicting asthma risk.
  • To evaluate current limitations in asthma genetics research.
  • To discuss these limitations within the context of genomic advances.

Main Methods:

  • Review and discussion of existing genomic data and approaches.
  • Analysis of technical limitations in current genetic studies.
  • Examination of fundamental conceptual deficiencies in asthma understanding.

Main Results:

  • Despite numerous genetic associations, systematic prediction of asthma risk remains low.
  • Technical and fundamental limitations impede comprehensive understanding.
  • Genomic advances highlight existing research gaps.

Conclusions:

  • Current genomic strategies are insufficient for predicting asthma risk.
  • A deeper understanding of asthma pathogenesis is required.
  • Further advancements in genomics are needed to overcome current limitations.