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Smoking topography and nicotine blood levels
D K Hatsukami1, R W Pickens, D S Svikis
1Department of Psychiatry, University of Minnesota 55455.
Addictive Behaviors
|January 1, 1988
Abstract:
Frequency and durational components of smoking topography were measured by a portable smoking device while 10 subjects smoked four cigarettes ad libitum in a non-laboratory environment. Nicotine blood levels were measured before and after smoking each cigarette and serial blood samples for determining nicotine metabolic half-life were obtained the following day. Results showed that change in pre- and post-cigarette nicotine levels and metabolic half-life for nicotine were not related to within-cigarette topography measures or nicotine yield of cigarette, but were significantly related to intercigarette interval.