Related Experiment Video
Updated: Nov 15, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
Published on: December 19, 2020
Tuberculous pericarditis with tamponade diagnosed concomitantly with COVID-19: a case report
Shiun Woei Wong1, Jessica Ke Xuan Ng1, Yew Woon Chia1
1Department of Cardiology, Tan Tock Seng Hospital, 11, Jalan Tan Tock Seng, 308433 Singapore.
Background:
Tuberculous pericarditis is a rare manifestation of tuberculosis infection. COVID-19 pandemic poses a challenge in detecting uncommon diseases.
Case Summary:
A 47-year-old man was admitted with symptoms of COVID-19 infection. Rapid progression of cardiomegaly on radiograph with clinical deterioration were suggestive of pericardial tamponade. Urgent pericardiocentesis revealed haemoserous fluid, elevated adenosine deaminase, and positive tuberculous (TB) polymerase chain reaction (PCR). He was started on anti-TB therapy and Remdesivir with marked improvement of symptoms. Repeat echocardiogram and CT thorax showed resolution of pericardial fluid, and the patient remained well on discharge.
Discussion:
This case highlights the difficulty in detecting a concomitant rare but important disease. The development of massive pericardial tamponade acutely is not pathognomonic for COVID-19, and a careful diagnostic process involving multi-modality imaging occurred to arrive at a diagnosis of tuberculosis.
Related Concept Videos
Pericarditis II: Clinical Features and Diagnostic Tests
Pericarditis III: Medical Management
Pericarditis IV: Nursing Management
Pericarditis I: Introduction
Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis III: Medical Management

