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Updated: Nov 15, 2025

Semi-High Throughput Screening for Potential Drought-tolerance in Lettuce Lactuca sativa Germplasm Collections
Published on: April 17, 2015
The genome sequence of Aloe vera reveals adaptive evolution of drought tolerance mechanisms
Shubham K Jaiswal1, Shruti Mahajan1, Abhisek Chakraborty1
1MetaBioSys Group, Department of Biological Sciences, Indian Institute of Science Education and Research Bhopal, Bhopal, Madhya Pradesh, India.
Abstract:
Aloe vera is a species from Asphodelaceae family having characteristics like drought resistance and numerous medicinal properties. However, the genetic basis of these phenotypes is yet unknown primarily due to unavailability of its genome sequence. Thus, we report the first Aloe vera genome sequence comprising of 12.93 Gbp and harboring 86,177 protein-coding genes. It is the first genome from Asphodelaceae family and the largest angiosperm genome sequenced and assembled till date. We also report the first genome-wide phylogeny of monocots including Aloe vera to resolve its phylogenetic position. The comprehensive comparative analysis of Aloe vera with other available high-quality monocot genomes revealed adaptive evolution in several genes of drought stress response, CAM pathway, and circadian rhythm and positive selection in DNA damage response genes in Aloe vera. This study provides clues on the genetic basis of evolution of drought stress tolerance capabilities of Aloe vera.
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