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Updated: Nov 15, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
Designing a screening battery for exercisers with Parkinson's disease
Lindsay V Slater1, Aleksandra Gebska2, Kiersten McCartney3
1Department of Physical Therapy, University of Illinois at Chicago, Chicago, IL, USA.
A new screening tool helps community exercise professionals quickly assess functional changes in people with Parkinson's disease (PD), improving exercise adherence and motivation.
Area of Science:
- Neurology
- Rehabilitation Science
- Exercise Physiology
Background:
- Parkinson's disease (PD) is a progressive neurodegenerative disorder impacting motor function.
- Functional decline in PD necessitates regular monitoring and tailored exercise interventions.
- Existing screening methods often pose barriers for community-based exercise professionals.
Purpose of the Study:
- To develop and validate a brief, easily administered functional screening battery for individuals with Parkinson's disease (PD).
- To create a tool for community exercise professionals to measure functional changes in PD patients.
- To enhance exercise adherence and motivation in individuals with PD through objective feedback.
Main Methods:
- A mixed-methods approach involving interviews with exercise professionals and persons with PD (n=57).
- Development of a screening battery requiring minimal equipment and under 20 minutes to administer.
- Repeated administration of the screening battery over 8-16 weeks with performance analysis using paired t-tests and Cohen's d effect sizes.
Main Results:
- The developed screening battery is time-efficient (<20 min), requires minimal equipment, and is suitable for group or individual settings.
- Persons with PD showed significant functional improvements in sit-to-stand (d=-0.71), 2-minute walk test (d=-3.83), and arm curls (d=-0.78).
- Objective feedback from the screening motivated participants and indicated potential for increased exercise adherence.
Conclusions:
- A brief, functional screening battery can be effectively implemented by community exercise professionals for individuals with PD.
- Objective assessment results serve as a motivator, potentially increasing exercise adherence and slowing functional decline.
- This tool aids in detecting functional deficits and tailoring exercise programs to improve quality of life in people with Parkinson's disease.
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