Vedolizumab Therapy in Refractory Microscopic Colitis: A Single Center Case Series

Area of Science:

• Gastroenterology
• Pathology

Background:

• Microscopic colitis (MC) presents as chronic watery diarrhea.
• Inflammation of the colon underlies the condition.
• Endoscopic examination often reveals normal colonic mucosa.

Purpose of the Study:

• To describe the key features of microscopic colitis.
• To highlight the diagnostic importance of histological examination in MC.

Main Methods:

• Review of endoscopic and histological findings in microscopic colitis.
• Analysis of diagnostic criteria for MC.

Main Results:

• Endoscopic evaluation of the colon in MC typically shows normal mucosa.
• Characteristic histological findings on biopsy are essential for diagnosing MC.

Conclusions:

• Microscopic colitis is diagnosed based on characteristic histologic findings from colonic biopsies.
• Despite normal endoscopic appearance, biopsy is crucial for MC diagnosis.