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Updated: Nov 15, 2025
08:03
Myelin Oligodendrocyte Glycoprotein MOG35-55 Induced Experimental Autoimmune Encephalomyelitis EAE in C57BL/6 Mice
Published on: April 15, 2014
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MOG-associated encephalitis following SARS-COV-2 infection
John Peters1, Saleh Alhasan1, Chantal B F Vogels2
1Department of Neurology, Yale University School of Medicine, 333 Cedar St. New Haven, CT, 06510, USA.
Multiple Sclerosis and Related Disorders
|March 1, 2021
Summary
COVID-19 infection can trigger rare neurologic conditions like MOG-antibody associated encephalitis. This steroid-responsive case highlights potential links between COVID-19 and autoimmune brain inflammation.
Area of Science:
- Neurology
- Infectious Diseases
- Immunology
Background:
- Neurologic manifestations of COVID-19 are diverse.
- Autoimmune encephalitis is a recognized complication of viral infections.
Observation:
- A patient presented with cognitive decline, headache, and fever post-COVID-19.
- Brain imaging revealed unilateral FLAIR hyperintensities and leptomeningeal enhancement.
Findings:
- The patient was diagnosed with MOG-antibody associated encephalitis.
- Symptoms showed significant improvement with steroid treatment.
Implications:
- This case suggests a potential association between COVID-19 and MOG-antibody associated encephalitis.
- Further research is warranted to understand the immunopathogenesis and management of post-COVID-19 autoimmune neurological disorders.
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