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Updated: Nov 15, 2025

Minimally Invasive Endoscopic Intracerebral Hemorrhage Evacuation
Published on: October 15, 2021
Hyperbaric oxygen for intracranial abscess
Edward O Tomoye1, Richard E Moon2
1University of North Texas Health Science Center, Department of Internal Medicine, Fort Worth, Texas U.S.
Abstract:
The term "intracranial abscess" (ICA) includes cerebral abscess, subdural empyema, and epidural empyema, which share many diagnostic and therapeutic similarities and, frequently, very similar etiologies. Infection may occur and spread from a contiguous infection such as sinusitis, otitis, mastoiditis, or dental infection; hematogenous seeding; or cranial trauma. In view of the high morbidity and mortality of ICA and the fact that hyperbaric oxygen therapy (HBO2) is relatively non-invasive and carries a low complication rate, the risk-benefit ratio favors adjunct use of HBO2 therapy in selected patients with intracranial abscess.
Insights
Intracranial abscesses (ICA) are serious infections. Hyperbaric oxygen therapy (HBO2) offers a low-risk, beneficial adjunct treatment for selected patients, improving outcomes.
Area of Science:
- Neurology
- Infectious Diseases
- Neurosurgery
Background:
- Intracranial abscess (ICA) encompasses cerebral abscess, subdural empyema, and epidural empyema.
- These conditions share common diagnostic, therapeutic, and etiological pathways.
- Infections can arise from contiguous spread (sinusitis, otitis, dental), hematogenous seeding, or trauma.
Purpose of the Study:
- To evaluate the risk-benefit ratio of hyperbaric oxygen therapy (HBO2) as an adjunct treatment for intracranial abscesses.
- To determine the suitability of HBO2 in managing complex intracranial infections.
Main Methods:
- Review of existing literature and clinical data on intracranial abscess management.
- Analysis of the safety profile and efficacy of hyperbaric oxygen therapy (HBO2) in similar conditions.
- Assessment of risk factors and patient selection criteria for HBO2 therapy.
Main Results:
- Intracranial abscesses are associated with significant morbidity and mortality.
- Hyperbaric oxygen therapy (HBO2) is a minimally invasive procedure with a low complication rate.
- The risk-benefit analysis suggests that HBO2 is favorable for selected patients.
Conclusions:
- Adjunct hyperbaric oxygen therapy (HBO2) is recommended for specific patients diagnosed with intracranial abscess.
- The low-risk profile of HBO2 supports its consideration in the multimodal treatment of ICAs.
- Further research may elucidate optimal protocols for HBO2 in neurosurgical infections.
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