Related Experiment Video
Updated: Nov 15, 2025

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report
Soheila Aminimoghaddam1, Narjes Afrooz2, Setare Nasiri2
1Department of Gynecology and Oncology, Iran University of Medical Sciences, Tehran, Iran. Aminimoghaddam.s@iums.ac.ir.
Background:
Pregnancy seems to increase the risk of thrombotic thrombocytopenic purpura (TTP) relapses and make the TTP more severe in any of the pregnancy trimesters, or even during the postpartum period.
Case Presentation:
This study highlights details of treating a COVID-19 pregnant patient who survived. This 21-year addicted White woman was admitted at her 29th week and delivered a stillbirth. She was transferred to another hospital after showing signs of TTP, which was caused by a viral infection.
Conclusion:
This viral infection caused fever and dyspnea, and the patient was tested positive for COVID-19 infection. A chest computed tomography scan showed diffuse multiple bilateral consolidations and interlobar septal thickening. She stayed at the Intensive Care Unit for 20 days and treated with plasmapheresis. As far as we know, this is the first report of a TTP pregnant patient with COVID-19 infection.
Related Concept Videos
Mitral Valve Prolapse III: Nursing Management
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Teratogenicity
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Pulmonary Embolism III: Nursing Management
Venous Thrombosis III: Interprofessional Care

