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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
Published on: September 26, 2013
Innate lymphoid cell subsets and their cytokines in autoimmune diseases
Asma Maleki1, Jamal Motallebzadeh Khanmiri1, Mohammad Khani Eshrat Abadi1
1Department of Hematology, School of Allied Medical Sciences, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Abstract:
Both the innate and adaptive arms of the immune system are involved in the development of autoimmune diseases. The main mechanism of disease is due to adaptive immune cells that are active against self-antigens. These cells can cause major damage to body tissues. Innate lymphoid cells (ILCs) are an important type of innate immune cell, whose role has been highlighted in recent years. ILCs are responsible for some of the inflammation in the pathogenesis of autoimmune diseases. In this review, we discuss the role of ILCs in the immune response, as well as their involvement in various autoimmune diseases.
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