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Pleural effusion as an indicator for the poor prognosis of COVID-19 patients

Xiao-Shan Wei1, Xu Wang1, Lin-Lin Ye1

  • 1Department of Respiratory and Critical Care Medicine, Union Hospital, Tongji Medical College Huazhong University of Science and Technology, Wuhan, China.

International Journal of Clinical Practice
|March 2, 2021
PubMed

Insights

Pleural effusion in Coronavirus Disease 19 (COVID-19) patients indicates severe illness, increased mortality, and longer recovery times. This finding highlights the need for special attention to these patients for better outcomes.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Radiology

Background:

  • Coronavirus Disease 19 (COVID-19) rapidly emerged as a global pandemic.
  • Understanding clinical manifestations in specific patient groups is crucial.

Purpose of the Study:

  • To investigate the clinical characteristics and outcomes of COVID-19 patients with pleural effusion.
  • To determine if pleural effusion is a prognostic indicator in COVID-19.

Main Methods:

  • Retrospective enrollment of COVID-19 patients from Union Hospital.
  • Classification into groups based on computed tomography (CT) scan findings of pleural effusion.
  • Comparison of clinical features, laboratory results, imaging, and outcomes between groups.

Main Results:

  • Pleural effusion was present in 9.19% of COVID-19 patients.
  • Patients with pleural effusion exhibited more severe or critical illness and higher mortality.
  • Longer hospital stays, prolonged viral shedding, and delayed lung inflammation resolution were observed in patients with pleural effusion.

Conclusions:

  • Pleural effusion in COVID-19 patients is associated with poor prognosis.
  • These patients require specialized clinical attention.
  • Pleural effusion may serve as a significant indicator of adverse outcomes in COVID-19.
Abstract

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