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Lumping and splitting: The need for precision medicine and "personomics" in endometrial cancer

Fiorella E Reyes-Baez1, Simone Garzon1, Andrea Mariani2

  • 1Department of Gynecology and Obstetrics, Mayo Clinic, Rochester, MN, USA.

Journal of Gynecologic Oncology
|March 2, 2021
PubMed
Abstract

No abstract available in PubMed .

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...