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Related Concept Videos

Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

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Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
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Pleural Effusion I: Introduction01:25

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Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
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Pleural Disorders: Types and Brief Description01:30

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The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
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Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

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Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
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Pleura of the Lungs01:13

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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
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Pneumonia II: Pathophysiology01:29

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The pathophysiology of pneumonia involves the following steps:
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Related Experiment Video

Updated: Nov 15, 2025

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
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Advances in pleural infection and malignancy.

Eihab O Bedawi1, Julien Guinde2, Najiib M Rahman1,3

  • 1Oxford Pleural Unit, Oxford Centre for Respiratory Medicine, Oxford University Hospitals, Oxford, UK.

European Respiratory Review : an Official Journal of the European Respiratory Society
|March 2, 2021
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Rising pleural infection incidence requires earlier diagnosis and treatment. Advances in pleural malignancy research streamline care, focusing on timely diagnosis and patient-centered management of malignant pleural effusion.

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Area of Science:

  • Pulmonology
  • Thoracic Medicine
  • Oncology

Background:

  • Pleural infection and malignancy are leading causes of pleural disease.
  • Recent advancements have improved scientific understanding in these fields.
  • The rising incidence of pleural infection is a significant concern.

Purpose of the Study:

  • To summarize recent literature on pleural infection and malignancy.
  • To inform current clinical practice in managing these pleural diseases.
  • To highlight advancements in diagnosis and treatment strategies.

Main Methods:

  • Review of recent scientific literature and clinical research.
  • Analysis of trends in incidence and outcomes for pleural infection.
  • Evaluation of streamlined patient pathways and treatment modalities for pleural malignancy.

Main Results:

  • Earlier diagnosis and risk stratification can improve outcomes for pleural infection.
  • Research facilitates efficient diagnosis and management of malignant pleural effusion.
  • Patient choice is crucial in treatment decisions for malignant pleural effusion.

Conclusions:

  • Increased awareness and timely intervention are key for pleural infection.
  • Optimized patient pathways reduce diagnostic and treatment delays in pleural malignancy.
  • Evidence supports patient-centered decision-making in managing malignant pleural effusion.