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Updated: Nov 15, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
[Pharmacotherapy in patients with loss of renal function]
T T Pieters1, A D R Huitema2, M B Rookmaaker1
1UMC Utrecht, afd. Nefrologie en Hypertensie, Utrecht.
Abstract:
When dosing renally excreted drugs in patients with kidney disease, it is important to have a reliable estimate of renal function. The estimated glomerular filtration rate (eGFR) is often used in the clinic, although this measure can be inaccurate in certain situations. Choosing the appropriate drug and dosage should therefore not be solely based on the eGFR. In this review, we discuss the physiology behind renal function estimation and drug dosing and propose a step by step approach to dosing renally excreted drugs in patients with kidney disease.
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