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Inverted internal limiting membrane flap technique for myopic macular hole: A meta-analysis
Irini Chatziralli1, Genovefa Machairoudia1, Dimitrios Kazantzis1
12nd Department of Ophthalmology, National and Kapodistian University of Athens, Athens, Greece.
Survey of Ophthalmology
|March 2, 2021
Summary
The inverted internal limiting membrane (ILM) flap technique effectively treats myopic macular holes (MH), achieving high closure rates. Visual acuity outcomes vary depending on whether retinal detachment (RD) is present.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- High myopia is a risk factor for macular holes (MH).
- The inverted internal limiting membrane (ILM) flap technique is a novel surgical approach for myopic MHs.
Purpose of the Study:
- To evaluate the anatomical and functional outcomes of the inverted ILM flap technique for myopic MHs.
- To compare outcomes in myopic MHs with and without retinal detachment (RD).
Main Methods:
- Meta-analysis of published studies on the inverted ILM flap technique.
- Analysis of MH closure rates and visual acuity improvement.
Main Results:
- High MH closure rates were observed (91.8%–97.1%) with the inverted ILM flap technique.
- Visual acuity improvement was notable, particularly in cases with retinal detachment (up to 95%).
Conclusions:
- The inverted ILM flap technique is effective for treating myopic MHs, with or without RD.
- Potential complications include MH reopening, RD, and other ocular issues.

