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Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
Systemic lupus erythematosus multiorgan flare with quiescent serologic markers
Jennifer Jane Gile1, Jaskanwal Deep Singh Sara2, Michael R Mueller3
1Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA Gile.Jennifer@mayo.edu.
Abstract:
Systemic lupus erythematosus (SLE) can affect almost every organ with differing degrees of severity. Typically, SLE activity is associated with hypocomplimentaemia and elevated double-stranded DNA (dsDNA) levels. We describe a case of a severe multiorgan lupus flare including lupus cerebritis, autoimmune haemolytic anaemia, lupus nephritis and lupus myopericarditis with normal complement and dsDNA levels. This highlights the importance of understanding the heterogeneous nature of SLE flares.
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