Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical Outcomes and Risk Factors for Surgical Failure Following Baerveldt Glaucoma Implant Surgery as a Primary Filtering Procedure.

Journal of clinical medicine·2026
Same author

Choroidal Detachment After Baerveldt Glaucoma Implant Surgery: Incidence and Risk Factors.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Long-term safety and efficacy of sepetaprost, with or without timolol, in patients with open-angle glaucoma or ocular hypertension: results from the randomised, phase 3 ANGEL-J2 study.

Japanese journal of ophthalmology·2026
Same author

Efficacy and safety of sepetaprost in patients with primary open-angle glaucoma or ocular hypertension: results from the randomised, phase 3 ANGEL-J1 study.

Japanese journal of ophthalmology·2026
Same author

Intravitreal Faricimab Prior to Direct Photocoagulation Improves Anatomical Outcomes in Focal Diabetic Macular Edema.

Journal of clinical medicine·2026
Same author

Effects of Ripasudil Hydrochloride Hydrate-Brimonidine Tartrate Fixed-Dose Combination Using Rho Kinase Inhibitor and Alpha2 Adrenergic Receptor Agonist on Aqueous Column in the Episcleral Vein: A Randomized, Double-Masked, Crossover Clinical Trial (ROCK Alpha-Aqua Study).

Journal of clinical medicine·2026

Related Experiment Video

Updated: Nov 15, 2025

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

2.0K

Computational fluid dynamics (CFD) simulation analysis on retinal gas cover rates using computational eye models

Makoto Gozawa1, Yoshihiro Takamura2, Tomoe Aoki2

  • 1Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, 23-3 Shimoaizuki, Matsuoka, Eiheiji, Yoshida, Fukui, 910-1193, Japan. makoto.gozawa@gmail.com.

Scientific Reports
|March 3, 2021
PubMed
Summary

This study used computational models to determine optimal patient positions after retinal detachment surgery. The supine position is best for inferior breaks, while other positions suit superior or peripheral breaks, improving surgical outcomes.

More Related Videos

Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

19.0K
Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies
06:16

Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies

Published on: July 28, 2023

2.9K

Related Experiment Videos

Last Updated: Nov 15, 2025

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
10:50

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches

Published on: June 21, 2022

2.0K
Doppler Optical Coherence Tomography of Retinal Circulation
10:46

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

19.0K
Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies
06:16

Author Spotlight: Unraveling the Pathogenesis of Age-Related Macular Degeneration and Discovering Potential Therapies

Published on: July 28, 2023

2.9K

Area of Science:

  • Ophthalmology
  • Biomedical Engineering
  • Fluid Dynamics

Background:

  • Rhegmatogenous retinal detachments (RRDs) are a significant cause of vision loss.
  • Pars plana vitrectomy (PPV) with gas tamponade is a common treatment for RRDs.
  • Postoperative positioning is crucial for successful gas tamponade and retinal reattachment.

Purpose of the Study:

  • To investigate the impact of intraocular gas volume and patient position on retinal gas cover rates.
  • To determine the optimal postoperative positions for different RRD configurations following PPV.
  • To provide data-driven recommendations for improving surgical outcomes in RRD treatment.

Main Methods:

  • Utilized computational fluid dynamic (CFD) software to model a pseudophakic eye.
  • Simulated varying intraocular gas volumes (10-90%) within the vitreous cavity.
  • Analyzed retinal gas cover rates in supine, sitting, lateral, and prone positions for different retinal break locations.

Main Results:

  • The supine position provided 100% retinal gas cover for the longest duration for inferior breaks or multiple breaks anterior to the equator.
  • Specific positions (sitting, lower temporal, lower nasal) were optimal for superior, temporal, and nasal breaks, respectively.
  • Retinal wall wettability was calculated to assess gas-fluid interactions.

Conclusions:

  • Patient positioning significantly influences the duration and extent of retinal gas cover after PPV for RRDs.
  • Tailoring postoperative position to the location of retinal breaks can maximize tamponade efficacy.
  • These findings can help optimize surgical strategies and potentially reduce the need for prolonged prone positioning.