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Updated: Nov 15, 2025

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Multilayered retinal pigment epithelial detachment: an optical coherence tomography angiography perspective
Dhanashree Ratra1, Samarth Mishra1
1Department of Vitreoretinal Diseases, Sankara Nethralaya, Chennai, India.
Abstract:
A new entity termed multilayered pigment epithelial detachment is seen to occur with the use of multiple intravitreal anti-VEGF agents. A distinct appearance of a spindle-shaped elevation with bands of hyporeflective and hyperreflective tissue is seen on optical coherence tomography. We describe a novel finding on optical coherence tomography angiography which includes a large type 1 choroidal neovascular membrane underlying this elevation. A large vascular network is seen. It is thought to be protective in nature and may prevent further degeneration.

