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Updated: Nov 15, 2025

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Artifacts and artifact removal in optical coherence tomographic angiography
Tristan T Hormel1, David Huang1, Yali Jia1,2
1Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA.
Optical coherence tomographic angiography (OCTA) imaging reveals retinal vasculature. This review details OCTA artifacts and removal strategies to improve measurement accuracy and image interpretation for better disease diagnosis.
Area of Science:
- Ophthalmology
- Medical Imaging
- Biomedical Engineering
Background:
- Optical coherence tomographic angiography (OCTA) is a key technology for 3D retinal vasculature imaging.
- OCTA aids in quantifying healthy vessels and diagnosing various retinal diseases.
- Artifacts in OCTA data can compromise measurement accuracy and image interpretation.
Purpose of the Study:
- To review common artifacts encountered in OCTA imaging.
- To discuss the sources of projection, motion, and signal reduction artifacts.
- To present strategies for artifact removal and compensation in OCTA data.
Main Methods:
- Literature review of OCTA artifacts and compensation techniques.
- Analysis of artifact sources including projection, motion, and signal reduction.
- Evaluation of strategies for artifact removal and correction.
Main Results:
- Identified common OCTA artifacts and their origins.
- Described methods for mitigating projection, motion, and signal reduction artifacts.
- Highlighted the importance of artifact compensation for accurate OCTA measurements.
Conclusions:
- Artifacts are a significant challenge in OCTA imaging.
- Effective artifact removal strategies are crucial for reliable OCTA data.
- Integrating hardware and software for artifact correction will enhance OCTA's clinical utility.
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