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Cardiovascular Factors Associated with Septic Shock Mortality Risks
Jelena Arnautovic1, Areej Mazhar2, Britni Souther2
1St. John Macomb, Department of Cardiovascular Medicine, Faculty, Warren MI.
Spartan Medical Research Journal
|March 3, 2021
Summary
Cardiovascular risk factors significantly impact septic shock mortality. Conditions like hypertension, heart failure, and elevated troponin levels increase death risk, highlighting the need for targeted cardiac care in sepsis management.
Area of Science:
- Critical Care Medicine
- Cardiology
- Infectious Disease
Background:
- Chronic health conditions increase sepsis and severe sepsis risks.
- Cardiovascular dysfunction is common in sepsis patients and impacts prognosis.
- Septic shock has the highest mortality risk, necessitating evaluation of cardiovascular risk factors.
Purpose of the Study:
- To assess the impact of cardiovascular risk factors on mortality in septic shock patients.
- To identify specific cardiovascular risks associated with higher mortality in septic shock.
Main Methods:
- Retrospective analysis of electronic health records from four hospital ICUs.
- Inclusion of septic shock patients admitted to the emergency department.
- Exclusion of patients with cardiopulmonary arrest or transfers from outside facilities.
Main Results:
- Deceased patients were more often male with histories of hypertension, congestive heart failure, coronary artery disease, or peripheral arterial diseases.
- Pre-admission beta-blocker use and higher APACHE II scores were noted in non-survivors.
- Elevated troponin levels and atrial fibrillation were significantly associated with higher mortality risks.
Conclusions:
- Prompt triage and tailored therapy to address cardiac dysfunction may improve survival in septic shock.
- Further research is needed to identify therapeutic targets for elevated troponin and atrial fibrillation to reduce mortality.
- Understanding cardiovascular risk factors is crucial for optimizing septic shock patient outcomes.
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