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Updated: Jun 30, 2026
Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
Diagnosis of central nervous system invasive aspergillosis in a liver transplant recipient using microbial cell-free
Akira A Shishido1, Alexander Vostal1, Romana Mayer2
1Division of Infectious Diseases, University of Maryland Medical Center, Baltimore, MD, USA.
Abstract:
Invasive aspergillosis (IA) is an important opportunistic infection among patients with liver disease and liver transplants. Diagnosis of IA may be challenging, especially among patients with central nervous system infection. Herein, we demonstrate the utility of next-generation sequencing of microbial cell-free DNA in the diagnosis of fungal brain abscess in a liver transplant recipient.
Insights
Next-generation sequencing of microbial cell-free DNA aids in diagnosing fungal brain abscesses in liver transplant patients. This advanced technique offers a valuable tool for identifying invasive aspergillosis (IA) in complex cases.
Area of Science:
- Medical Mycology
- Transplant Infectious Diseases
- Molecular Diagnostics
Background:
- Invasive aspergillosis (IA) is a significant opportunistic infection in liver disease and transplant patients.
- Diagnosing IA, particularly with central nervous system involvement, presents considerable challenges.
