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Related Experiment Videos

Methyldopa hypersensitivity can mimic acute toxic enterocolitis.

B A Young¹, M J Girotti

¹Department of Pharmaceutical Services, Toronto General Hospital, Ont.

Canadian Journal of Surgery. Journal Canadien De Chirurgie

|May 1, 1988

Summary

This summary is machine-generated.

Methyldopa, used for hypertension, can cause rare but severe enterocolitis. Discontinuing the drug provided immediate relief, suggesting it as a cause for this hypersensitivity reaction.

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Area of Science:

Pharmacology
Gastroenterology
Internal Medicine

Background:

Methyldopa is a common antihypertensive medication.
Its known hypersensitivity reactions include Coombs' test positivity and hemolytic anemia.
Acute toxic enterocolitis is an infrequent but serious adverse reaction.