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Related Experiment Video

Updated: Nov 15, 2025

Delayed Intramyocardial Delivery of Stem Cells after Ischemia Reperfusion Injury in a Murine Model
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Proposed delay for safe surgery after COVID-19.

Joshua G Kovoor1,2, N Ann Scott2, David R Tivey3,4

  • 1University of Adelaide, Adelaide, South Australia, Australia.

ANZ Journal of Surgery
|March 3, 2021
PubMed
Summary

Patients should delay minor surgery for at least 4 weeks and major surgery for 8-12 weeks after COVID-19 infection. This ensures adequate recovery and optimizes surgical safety for better patient outcomes.

Keywords:
COVID-19SARS-CoV-2inflammationlong-termsurgerysymptom

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Area of Science:

  • Medical Research
  • Surgical Safety
  • Infectious Diseases

Background:

  • Post-COVID-19 long-term effects can compromise surgical safety.
  • Evidence-based guidance is needed for optimal patient recovery periods before surgery after COVID-19.

Purpose of the Study:

  • To evaluate the literature on post-COVID-19 recovery.
  • To provide evidence-based recommendations for surgical delay after SARS-CoV-2 infection.

Main Methods:

  • Rapid review of literature combined with expert clinical advice.
  • Searched MEDLINE, medRxiv, and grey literature up to October 4, 2020.
  • Evidence levels stratified using the National Health and Medical Research Council hierarchy.

Main Results:

  • 20 studies (12 peer-reviewed) were included; no randomized trials.
  • Common symptoms include fatigue and breathlessness, persisting for months.
  • Pulmonary complication and mortality risks may be lowest 4 weeks post-infection for elective cancer surgery.

Conclusions:

  • Delay minor surgery for at least 4 weeks and major surgery for 8-12 weeks after SARS-CoV-2 diagnosis.
  • Ensure comprehensive preoperative and ongoing assessments for informed clinical decisions.
  • Prioritize patient outcomes when determining surgical timing post-COVID-19.