Electrochemical Fluorescence Switch of Organic Fluorescent or Fluorogenic Molecules
Manon Guille-Collignon1, Jérôme Delacotte1, Frédéric Lemaître1
1PASTEUR, Département de Chimie, Ecole Normale Supérieure, PSL University, Sorbonne Université, CNRS, 75005, Paris, France.
Chemical Record (New York, N.Y.)
|March 3, 2021
Summary
Electrochemistry is revolutionizing organic molecule fluorescence, enabling new probes and instrumentation for molecular-level insights. This review highlights recent advancements in fluorescence modulation for bioanalysis.
Area of Science:
- Electrochemistry
- Organic Chemistry
- Analytical Chemistry
Background:
- Fluorescence modulation of organic molecules is a rapidly advancing field.
- Electrochemistry offers precise control over molecular properties.
- Recent work focuses on developing new probes and analytical techniques.
Purpose of the Study:
- To review prominent recent works on electrochemically controlled fluorescence modulation.
- To highlight advancements in instrumentation for molecular-level analysis.
- To scrutinize key considerations in probe design and modulation.
Main Methods:
- Review of recent scientific literature.
- Analysis of studies employing electrochemical methods for fluorescence control.
- Examination of instrumentation development for time- and space-resolved measurements.
Main Results:
- Significant progress in designing novel fluorescent and fluorogenic probes.
- Development of sophisticated instrumentation for molecular analysis.
- Exploration of reversible and irreversible fluorescence switching mechanisms.
Conclusions:
- Electrochemical fluorescence modulation is a key area for bioanalysis.
- Continued research promises enhanced molecular-level understanding and applications.
- Interdisciplinary approaches are crucial for future advancements.
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