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Gorham-Stout Disease Resulting in Spinal Deformity Treated by Fusion Surgery Combined With Everolimus Therapy: A Case
Akira Toga1, Kota Watanabe, Satoshi Suzuki
1Department of Orthopedic Surgery, Keio University School of Medicine, Shinjuku, Tokyo, Japan.
Case:
Gorham-Stout disease (GSD) is a rare disorder characterized by progressive localized osteolysis and lymphatic malformation. A 26-year-old woman with GSD presented to our hospital with a Cobb angle of 100° and a kyphosis angle of 88°. Everolimus therapy was initiated to control the disease prior to surgery. After halo-gravity traction for 4 weeks, we performed anterior and posterior spinal fusion. Postoperative computed tomography revealed satisfactory bone union and no significant loss of correction 1 year post-surgery.
Conclusion:
This case suggests that anterior and posterior spinal fusion combined with everolimus therapy can be a therapeutic option for GSD.
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