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Updated: Nov 15, 2025

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
An Unusual Case of Retroperitoneal Plexiform Neurofibromas Found in a Trauma Patient
Allen Mao1, Hunaid N Rana1, Mohamed Elramah1
1Radiology, USA Health University Hospital, Mobile, USA.
Abstract:
The spectrum of presentation for patients who have neurofibromatosis type 1 (NF1), or von Recklinghausen disease, is very diverse due to a phenomenon known as variable expressivity. Patients may or may not present with cutaneous lesions or central nervous system (CNS) manifestations. However, multiple neurofibromas are the pathognomonic hallmark of NF1. The most common abdominal neoplasm is plexiform neurofibromas that affect the retroperitoneal region. We highlight the hospital course of a patient with an unknown history of NF1 who presented for head trauma with plexiform neurofibromas found incidentally on imaging. The radiographic features of neurofibromas are described in addition to the discussion of management and prognosis of NF1.

