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Recent advances in managing primary hypertension

Ioannis Leontsinis1, Manos Mantzouranis1, Panagiotis Tsioufis1

  • 1First Cardiology Clinic, Medical School, National and Kapodistrian University of Athens, Hippokration Hospital, 108 Vas. Sofias Ave, 11527, Athens, Greece.

Faculty Reviews
|March 4, 2021
PubMed

Insights

Managing hypertension effectively requires lower blood pressure targets and personalized treatment strategies. This review explores modern approaches, including new therapies and technologies, to address undertreatment and improve cardiovascular outcomes.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Public Health

Background:

  • Hypertension is a primary global risk factor for cardiovascular disease and mortality.
  • Current antihypertensive medications are effective, yet undertreatment and resistant hypertension persist.
  • Evidence supports more aggressive blood pressure control in specific patient populations.

Purpose of the Study:

  • To review current perspectives and emerging strategies in hypertension management.
  • To highlight novel therapeutic options, technological advancements, and interventional therapies.
  • To discuss major concerns and research findings in hypertension control.

Main Methods:

  • Review of recent scientific literature and epidemiological data on hypertension.
  • Analysis of evolving concepts in blood pressure measurement and risk stratification.
  • Exploration of innovative pharmaceutical and interventional treatment modalities.

Main Results:

  • Optimal blood pressure targets are increasingly recognized as lower, especially for high-risk individuals.
  • Out-of-office blood pressure monitoring is crucial for accurate assessment and treatment guidance.
  • Individualized treatment plans are essential to balance efficacy and prevent overtreatment.
  • Undertreatment remains a significant challenge, linked to adherence issues and resistant hypertension.

Conclusions:

  • Modern hypertension management necessitates a shift towards lower BP targets and personalized care.
  • Innovative technologies and therapies offer new avenues for controlling difficult-to-manage hypertension.
  • Addressing undertreatment and optimizing adherence are critical for reducing cardiovascular morbidity and mortality.

Keywords:
difficult to treat hypertensionhypertensionhypertension managementneuromodulationnovel antihypertensivesresistant hypertension

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