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Related Concept Videos

Sample Preparation for Analysis: Overview01:21

Sample Preparation for Analysis: Overview

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Sample preparation is an essential step in the analytical process. It involves preparing a sample so that it can be analyzed accurately. The goal is to extract the analyte, the substance you want to measure, from the sample while removing any components that may interfere with the analysis. Sample preparation techniques vary depending on the physical state of the sample.
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Accurate analysis of complex samples often requires advanced preparation techniques to achieve reliable and reproducible results. Samples containing inorganic or organic materials can be challenging to dissolve or decompose effectively. Standard sample preparation methods include acid digestion, fusion, dry ashing, and wet digestion.
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Capturing Actively Produced Microbial Volatile Organic Compounds from Human-Associated Samples with Vacuum-Assisted Sorbent Extraction
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Recent applications of microextraction sample preparation techniques in biological samples analysis.

Seyed Mosayeb Daryanavard1, Hesane Zolfaghari1, Abbi Abdel-Rehim2

  • 1Department of Chemistry, Faculty of Science, University of Hormozgan, Bandar-Abbas, Iran.

Biomedical Chromatography : BMC
|March 4, 2021
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Summary

Microextraction techniques are crucial for preparing biological samples like urine, blood, and saliva for analysis. This review details methods for analyte enrichment, improving accuracy in drug and substance detection.

Keywords:
biological samplesmicroextraction techniquessample preparation

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Area of Science:

  • Analytical Chemistry
  • Biochemistry
  • Forensic Science

Background:

  • Analysis of biological samples (blood, urine, saliva) is challenged by interfering substances.
  • Effective sample preparation is vital for accurate analyte detection using analytical instruments.
  • Microextraction techniques offer efficient solutions for separating and purifying biological samples.

Purpose of the Study:

  • To provide a comprehensive review of microextraction techniques for biological sample preparation.
  • To summarize recent literature (2017-present) on microextraction applications in urine, blood, and saliva.
  • To detail the objectives and merits of various microextraction methods for different biological matrices.

Main Methods:

  • Literature review focusing on microextraction techniques.
  • Analysis of methods for separation, purification, and enrichment of analytes.
  • Examination of recent applications in quantitative and qualitative analysis of biological samples.

Main Results:

  • Microextraction techniques play a key role in overcoming challenges in biological sample analysis.
  • Recent studies demonstrate innovative applications of microextraction for analyte preconcentration.
  • Various techniques are effective for urine, blood, and saliva sample preparation.

Conclusions:

  • Microextraction is indispensable for effective biological sample preparation.
  • The review highlights advancements and applications of microextraction in recent years.
  • Understanding microextraction methods is crucial for accurate analysis of biological samples.