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Updated: Nov 15, 2025
Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection
Published on: February 1, 2022
A stable biosensor for organophosphorus pesticide detection based on chitosan modified graphene
Jianhua Zhang1, Huaying Hu1, Pengchang Wang1
1Key Laboratory of Advanced Display and System Applications, Ministry of Education, Shanghai University, Shanghai, China.
Abstract:
An acetylcholinesterase (AChE) biosensor was successfully fabricated with a stable structure and high detection accuracy. Graphene (Gra) nanofragments modified with chitosan (CS) and AChE were successively drip coated on the surface of a glassy carbon electrode via a layer-by-layer assembly method. The concentration range of the sensor to detect dichlorvos was 0.1-100,000 nM, and the limit of detection was 54 pM. CS was used to modify Gra for the first time, which enhanced the mechanical flexibility of these Gra nanostructures, significantly improving the stability and detection accuracy of this sensor.
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