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Analytical determinations of luteolin.

Alvaro Y Tesio1, Sebastian N Robledo2

  • 1Centro de Investigación y Desarrollo en Materiales Avanzados y Almacenamiento de Energía de Jujuy (CIDMEJu), Centro de Desarrollo Tecnológico General Savio, Palpalá, Jujuy, Argentina.

Biofactors (Oxford, England)
|March 4, 2021
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Summary

This review covers analytical methods for quantifying luteolin, a bioactive flavonoid, focusing on recent advancements. It compares techniques based on sensitivity, cost, and complexity for health applications.

Keywords:
antioxidantchromatographyelectroanalytical chemistryflavonoidluteolin

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Area of Science:

  • Biochemistry
  • Analytical Chemistry
  • Pharmacology

Background:

  • Plants produce primary and secondary metabolites; flavonoids are key secondary metabolites.
  • Luteolin, a flavone, is a highly bioactive flavonoid with significant health benefits.
  • Antioxidant properties of luteolin are increasingly important, driving research into its quantification.

Purpose of the Study:

  • To provide a comprehensive overview of analytical determination techniques for luteolin.
  • To focus on advancements and methodologies reported in the last five years.
  • To critically evaluate various quantification techniques.

Main Methods:

  • Review of literature on analytical methods for luteolin quantification.
  • Comparative analysis of techniques based on selectivity, sensitivity, cost, and time.
  • Discussion of operational complexity and reagent requirements for different methods.

Main Results:

  • Identified and analyzed diverse analytical techniques for luteolin measurement.
  • Detailed comparison of advantages and disadvantages of each method.
  • Highlighted recent trends and innovations in luteolin quantification.

Conclusions:

  • Accurate luteolin quantification is crucial for understanding its health benefits.
  • The choice of analytical technique depends on specific application needs and resource availability.
  • Ongoing research continues to refine and develop more efficient luteolin determination methods.