Predictors of erectile dysfunction after transperineal template prostate biopsy

Area of Science:

• Urology
• Men's Health
• Sexual Medicine

Background:

• Transperineal template prostate biopsy (TTPB) is a common procedure for prostate cancer diagnosis.
• Erectile dysfunction (ED) is a potential complication following prostate biopsy, impacting quality of life.
• Understanding predictors of post-biopsy ED is crucial for patient counseling and management.

Purpose of the Study:

• To determine the incidence of erectile dysfunction (ED) after transperineal template prostate biopsy (TTPB).
• To identify contributing factors, particularly age, associated with ED following TTPB.

Main Methods:

• Prospective study involving 576 males undergoing TTPB.
• Sexual Health Inventory for Men (SHIM) questionnaires administered pre-biopsy and at 1, 3, and 9 months post-procedure.
• Multivariable logistic regression analysis to identify predictors of SHIM score changes.

Main Results:

• A decline in sexual function (ED) was reported by 31% of eligible males within 4 weeks post-TTPB.
• Older age was the strongest predictor of ED, with increased probability at ages 60 and 70.
• Predicted probability of new-onset ED within 4 weeks post-TTPB was 6.7% at age 50, 26% at age 60, and 31% at age 70.

Conclusions:

• Older age is an independent predictor of immediate ED after TTPB in sexually active men.
• This association holds true even for men without pre-existing ED.
• Findings are vital for counseling men undergoing TTPB regarding potential ED risks.