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Related Experiment Video

Updated: Nov 15, 2025

Focal Laser Ablation of Prostate Cancer: An Office Procedure
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Aquablation for benign prostatic obstruction: Single center technique evolution and experience.

Muhieddine Labban1, Mazen Mansour1, Nicolas Abdallah1

  • 1Division of Urology, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

Investigative and Clinical Urology
|March 4, 2021
PubMed
Summary

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Future oncology (London, England)·2025

Aquablation, a novel ultrasound-guided waterjet prostate tissue ablation, demonstrates safety and efficacy. This study shows good surgical and functional outcomes with low adverse events in its early adoption phase.

Area of Science:

  • Urology
  • Minimally Invasive Surgery
  • Medical Technology

Background:

  • Benign prostatic hyperplasia (BPH) is a common condition requiring treatment.
  • Aquablation offers a new approach to prostatic tissue ablation using real-time ultrasound guidance.
  • Understanding the early outcomes of Aquablation is crucial for its clinical adoption.

Purpose of the Study:

  • To evaluate the perioperative surgical and functional outcomes of Aquablation.
  • To assess the safety and efficacy of Aquablation in a tertiary care setting.
  • To analyze adverse events and trends in hemoglobin drop during the adoption phase of Aquablation.

Main Methods:

  • Prospective study of consecutive patients undergoing Aquablation.
  • Collection of patient demographics, voiding parameters, and prostate disease variables.
Keywords:
Lower urinary tract symptomsProstatic hyperplasiaRobotic surgical proceduresTherapy

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  • Analysis of surgical outcomes, functional results, and 3-month adverse events, including hemoglobin drop and hemostasis methods.
  • Main Results:

    • Fifty-nine patients underwent Aquablation with a mean procedure time of 48.5 minutes.
    • Average hemoglobin drop was -1.7 ng/dL; average catheterization and hospital stay were 2.1 and 2.2 days, respectively.
    • Significant improvement in functional outcomes and a -36.6% drop in PSA at 3 months, with a 22.0% overall adverse event rate (mostly low-grade).

    Conclusions:

    • Aquablation is a safe and effective procedure for treating BPH.
    • The study confirms positive surgical and functional outcomes during the initial adoption of Aquablation.
    • Low rates of re-hospitalization and predominantly low-grade complications support Aquablation's safety profile.