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[Abnormal erythrocyte membrane gangliosides in alcoholism]
U Haselhorst1, I Beyer, H Schenk
1Institut für Pathologische Biochemie, Medizinische Akademie, Magdeburg, G.D.R.
Drug and Alcohol Dependence
|February 1, 1988
Abstract:
The pattern of gangliosides in membranes of erythrocytes was examined in healthy donors and in alcoholic subjects. Seven different gangliosides could be detected. In healthy donors the following pattern was found: GM3 = 17.6%, SPG = 43.1%, GD3 = 9.1%, GD1a = 12.8%, FucGD1b = 5.2%, GT1b = 6.7% and GX = 5.7%. The GM3 and FucDG1b fraction were decreased statistically significantly in alcoholics.