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Related Concept Videos

Proteomics01:33

Proteomics

8.8K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
8.8K

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Related Experiment Video

Updated: Nov 15, 2025

A Method for Targeted 16S Sequencing of Human Milk Samples
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Human milk proteome: what's new?

Kelly A Dingess1,2, Cheng Li3, Jing Zhu3

  • 1Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht.

Current Opinion in Clinical Nutrition and Metabolic Care
|March 4, 2021
PubMed
Summary
This summary is machine-generated.

Human milk proteomics reveals novel insights into milk proteins, peptides, and their modifications. Understanding these complex components is crucial for infant nutrition and health.

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Area of Science:

  • Proteomics
  • Human milk composition
  • Infant nutrition

Background:

  • Human milk proteome is complex and multifunctional.
  • Recent studies explore factors influencing milk proteins and peptides.

Purpose of the Study:

  • Review novel characteristics of the human milk proteome.
  • Examine recent findings in human milk proteomics.

Main Methods:

  • Mass spectrometry advancements enable deeper proteome identification.
  • Analysis of protein and peptide profiles.

Main Results:

  • Human milk proteome expanded with insights into posttranslational modifications (PTMs).
  • Major protein profiles are similar across healthy women and infants.
  • Limited data exists for vulnerable infants or mothers with infections.

Conclusions:

  • Technological advances enhance human milk proteome characterization.
  • Further research needed on vulnerable populations and functional roles of milk components.