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Relapsing polychondritis associated with heart block.
J F de Carvalho1, L C Behrmann Martins, A F Cardoso
1Institute for Health Sciences from Federal University of Bahia, Salvador, Bahia, Brazil. jotafc@gmail.com.
European Review for Medical and Pharmacological Sciences
|March 4, 2021
Summary
Relapsing polychondritis (RP) can cause heart block (HB). A rare case of RP with heart block was successfully treated with methylprednisolone pulse therapy, avoiding pacemaker insertion.
Area of Science:
- Cardiology
- Rheumatology
- Immunology
Background:
- Relapsing polychondritis (RP) is a rare systemic autoimmune disease.
- Heart block (HB) is a potential, serious complication of RP.
- Literature review identified 10 studies on RP and HB, with limited treatment data.
Observation:
- A case of a patient with relapsing polychondritis developed heart block.
- The patient's heart block was successfully treated with high-dose methylprednisolone pulse therapy.
- This treatment avoided the need for pacemaker implantation.
Findings:
- Most reported RP-associated HB cases occurred in males aged 30-66.
- RP was active at the time of HB onset in most patients.
- Glucocorticoids were frequently used, and pacemakers were inserted in some cases.
Implications:
- Glucocorticoid pulse therapy may be an effective treatment for heart block in RP patients.
- This approach could potentially prevent pacemaker insertion in select cases.
- Further research is warranted to confirm the efficacy of this treatment strategy.
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