Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Nov 15, 2025

Simple Continuous Glucose Monitoring in Freely Moving Mice
03:25

Simple Continuous Glucose Monitoring in Freely Moving Mice

Published on: February 24, 2023

6.8K

Medical Food Assessment Using a Smartphone App With Continuous Glucose Monitoring Sensors: Proof-of-Concept Study.

Hector Roux de Bézieux1,2,3, James Bullard1, Orville Kolterman1

  • 1Pendulum Therapeutics, Inc, San Francisco, CA, United States.

JMIR Formative Research
|March 4, 2021
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Trajectory inference across multiple conditions with condiments.

Nature communications·2024
Same author

Increased circulating butyrate and ursodeoxycholate during probiotic intervention in humans with type 2 diabetes.

BMC microbiology·2022
Same author

A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex.

Nature·2021
Same author

Butyrate-producing human gut symbiont, <i>Clostridium butyricum</i>, and its role in health and disease.

Gut microbes·2021
Same author

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia.

Science advances·2020
Same author

Improvements to postprandial glucose control in subjects with type 2 diabetes: a multicenter, double blind, randomized placebo-controlled trial of a novel probiotic formulation.

BMJ open diabetes research & care·2020

Continuous glucose monitoring (CGM) devices and smartphone apps enable remote collection of glucose data, reducing clinical study burdens. This pilot study demonstrates their potential for real-world glucose monitoring without clinic visits.

Area of Science:

  • Biomedical Engineering
  • Digital Health
  • Endocrinology

Background:

  • Wearable biosensors, smartphones, and telemedicine are transforming clinical research.
  • Continuous glucose monitoring (CGM) devices offer clinical-grade glucose measurements, widely adopted for diabetes management.
  • Health apps are increasingly used by individuals for self-care and monitoring.

Purpose of the Study:

  • To investigate the feasibility of collecting robust, real-time, annotated glucose data remotely for clinical studies.
  • To assess the impact of a proprietary synbiotic on glucose control using novel remote monitoring technologies.

Main Methods:

  • A 6-week, double-blind, placebo-controlled, 2x2 cross-over pilot study (n=6) using self-administered meal-tolerance tests.
  • Abbott Freestyle Libre CGM devices linked to a smartphone app with a visual diet log were used for primary endpoint measurement.
Keywords:
clinical trialscontinuous glucose monitoringdiabeteslifestyle modificationmobile apptelemedicine

More Related Videos

Iterative Development of an Innovative Smartphone-Based Dietary Assessment Tool: Traqq
04:54

Iterative Development of an Innovative Smartphone-Based Dietary Assessment Tool: Traqq

Published on: March 19, 2021

4.9K
Home-Based Monitor for Gait and Activity Analysis
07:24

Home-Based Monitor for Gait and Activity Analysis

Published on: August 8, 2019

7.0K

Related Experiment Videos

Last Updated: Nov 15, 2025

Simple Continuous Glucose Monitoring in Freely Moving Mice
03:25

Simple Continuous Glucose Monitoring in Freely Moving Mice

Published on: February 24, 2023

6.8K
Iterative Development of an Innovative Smartphone-Based Dietary Assessment Tool: Traqq
04:54

Iterative Development of an Innovative Smartphone-Based Dietary Assessment Tool: Traqq

Published on: March 19, 2021

4.9K
Home-Based Monitor for Gait and Activity Analysis
07:24

Home-Based Monitor for Gait and Activity Analysis

Published on: August 8, 2019

7.0K
  • Data collection occurred over 40 days, averaging 3000 data points per subject.

    • Main Results:

    • All participants completed the study, successfully using CGM devices and the associated app.
    • No adverse events were reported; participants reported high satisfaction (8.25/10) with the study.
    • The study demonstrated the ability to detect meaningful changes in postprandial glucose response in real-world settings, despite limitations in statistical power.

    Conclusions:

    • CGM devices integrated with a smartphone app provide comprehensive glucose monitoring without requiring clinic visits.
    • This approach reduces participant burden and study costs while enabling remote integration of diverse data types.
    • The findings support the utility of CGM and digital health tools for future large-scale clinical research in diabetes.