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Updated: Nov 15, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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Biosynthesis of 6-Hydroxymellein Requires a Collaborating Polyketide Synthase-like Enzyme

Lukas Kahlert1, Miranda Villanueva1,2, Russell J Cox1

  • 1Institute for Organic Chemistry and BMWZ, Leibniz Universität Hannover, Schneiderberg 38, 30167, Hannover, Germany.

Angewandte Chemie (International Ed. in English)
|March 4, 2021
PubMed

Keywords:
iterative polyketide synthaseketoreductasemelleinterreintrans-acting domain

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