Related Experiment Video
Updated: Nov 15, 2025
10:47
Rapid Detection of Neurodevelopmental Phenotypes in Human Neural Precursor Cells NPCs
Published on: March 2, 2018
10.3K
Xenopus models suggest convergence of gene signatures on neurogenesis in autism
Kristen J Brennand1, Michael E Talkowski2
1Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06511, USA; Department of Genetics, Yale University School of Medicine, New Haven, CT 06511, USA.
Neuron
|March 4, 2021
Abstract:
Willsey et al. dissect phenotypes associated with in vivo disruption of ten ASD-associated genes using a hypothesis-free, parallelized approach in Xenopus tropicalis. These studies continue to implicate cortical neurons in ASD pathogenesis and suggest a convergence on functions related to neurogenesis.
