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Pregnancy in Pateints With Exstrophy-Epispadias Complex: Are Higher Rates of Complications and Spontaneous Abortion
Yesica Quiroz1, Erika Llorens1, Rosa Novoa1
1Urology Department, Fundació Puigvert, Barcelona, Spain.
Urology
|March 4, 2021
Summary
Women with exstrophy-epispadias complex (EEC) can achieve spontaneous pregnancies but face a higher risk of miscarriage. Specialized multidisciplinary care is crucial for managing pregnancy complications in these patients.
Area of Science:
- Urology
- Gynecology
- Reproductive Medicine
Background:
- Exstrophy-epispadias complex (EEC) is a rare congenital condition affecting the genitourinary and reproductive systems.
- Pregnancy outcomes and potential complications in female EEC patients are not well-documented.
Purpose of the Study:
- To characterize pregnancies in female patients with EEC.
- To assess the risk of spontaneous abortion and other complications during pregnancy and postpartum.
Main Methods:
- Retrospective review of 37 female patients with EEC treated at a reference center.
- Analysis of pregnancy outcomes, including successful pregnancies, miscarriages, and maternal/newborn complications.
- Descriptive statistics were employed.
Main Results:
- 17 pregnancies occurred in 8 patients, with 88.2% spontaneous.
- A miscarriage rate of 41.2% was observed.
- Urinary tract infections (41.6%) and genital prolapse (62.5%) were common postpartum complications; no newborn malformations were reported.
Conclusions:
- Female EEC patients can conceive spontaneously but have an elevated risk of miscarriage.
- Integrated, multidisciplinary monitoring is essential to mitigate pregnancy-related risks and complications.
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