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The tumor microenvironment shapes the molecular characteristics of exhausted CD8+ T cells

Hongcheng Cheng1, Kaili Ma2, Lianjun Zhang2

  • 1Suzhou Institute of Systems Medicine, Suzhou, Jiangsu, 215123, China; Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, 100005, Beijing, China; Key Laboratory of Synthetic Biology Regulatory Element, Chinese Academy of Medical Sciences, Beijing, China.

Cancer Letters
|March 4, 2021
PubMed

Keywords:
ImmunotherapyInhibitory receptorsT cell exhaustionTranscriptional factorsTumor microenvironment factors

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