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Related Experiment Video

Updated: Nov 15, 2025

Multimodality Diagnosis of Mesenteric Ischemia
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Colon ischemia: A comprehensive review.

Antonella Maimone1, Antonella De Ceglie1, Peter D Siersema2

  • 1Department of Gastroenterology, General Hospital, Sanremo, IM, Italy.

Clinics and Research in Hepatology and Gastroenterology
|March 4, 2021
PubMed
Summary
This summary is machine-generated.

Colon ischemia (CI) is often misdiagnosed due to non-specific symptoms. Prompt diagnosis and multidisciplinary treatment are vital for severe cases to improve outcomes and reduce mortality.

Keywords:
Colon ischemiaColonoscopyPathophysiologyTreatment

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Area of Science:

  • Gastroenterology
  • Internal Medicine

Background:

  • Clinical and endoscopic features of colon ischemia (CI) are non-specific, leading to underdiagnosis.
  • Mild CI cases often resolve spontaneously, and severe CI requires prompt recognition and therapy for favorable outcomes.
  • Current guidelines lack recommendations for long-term CI management and endoscopic follow-up for strictures.

Purpose of the Study:

  • To review the definition, etiology, and presentation patterns of colon ischemia.
  • To highlight management strategies based on disease severity, including pharmacological and endoscopic approaches.
  • To emphasize the importance of prompt diagnosis and multidisciplinary care for severe CI.

Main Methods:

  • Literature review focusing on colon ischemia.
  • Analysis of clinical and endoscopic presentations.
  • Evaluation of current management guidelines and treatment outcomes.

Main Results:

  • CI is correctly identified in only 9% of patients at presentation.
  • Severe CI necessitates prompt diagnosis, therapy, and identification of underlying causes for better outcomes.
  • Management differs significantly between mild (conservative) and severe (potentially surgical) CI.

Conclusions:

  • Accurate diagnosis and timely, multidisciplinary management are crucial for severe CI.
  • Pharmacological and endoscopic interventions, tailored to disease severity, can improve outcomes.
  • Further research is needed on long-term CI management and endoscopic surveillance for complications like strictures.