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Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Psychiatry

Background:

  • Early life stress (ELS) significantly affects brain development and behavior.
  • Understanding ELS is crucial for addressing public health crises and health inequities.
  • Resting-state functional magnetic resonance imaging (fMRI) advances the study of early brain development.

Purpose of the Study:

  • To review the application of fMRI in examining ELS effects on infant neurodevelopment.
  • To identify key areas for future research in this field.

Main Methods:

  • Review of existing literature on fMRI studies of early life stress.
  • Analysis of neurodevelopmental outcomes in infants exposed to ELS.

Main Results:

  • fMRI has provided novel insights into brain functioning and organization in infants.
  • ELS can alter neurodevelopmental trajectories relevant to psychiatric disorders.

Conclusions:

  • fMRI is a valuable tool for investigating the impact of ELS on infant brains.
  • Future research requires larger, powered studies with greater inclusion of diverse populations.