Complete Genome Sequence of Staphylococcus aureus Strain 834, Isolated from a Septic Patient in Japan

Hisaya K Ono1,2, Yasunori Suzuki3, Hiroaki Kubota4

  • 1Laboratory of Zoonoses, Kitasato University School of Veterinary Medicine, Towada, Japan.

Insights

We sequenced the complete genome of the virulent and methicillin-resistant *Staphylococcus aureus* strain 834 from a Japanese septic patient. This provides a valuable resource for understanding this dangerous pathogen.

Area of Science:

  • Microbiology
  • Genomics
  • Infectious Diseases

Background:

  • *Staphylococcus aureus* is a significant human pathogen.
  • Methicillin resistance and high virulence contribute to its clinical threat.
  • Understanding the genetic basis of these traits is crucial for developing new treatments.

Purpose of the Study:

  • To report the complete genome sequence of *Staphylococcus aureus* strain 834.
  • To provide a genomic resource for studying virulence and antibiotic resistance in *S. aureus*.

Main Methods:

  • Whole-genome sequencing of *Staphylococcus aureus* strain 834.
  • Bioinformatic analysis and genome annotation.

Main Results:

  • The complete genome sequence of strain 834 was determined.
  • The genome comprises a chromosome (2,838,668 bp) and a plasmid (24,653 bp).
  • Genome annotation identified 2,670 coding sequences, 16 rRNAs, and 61 tRNAs.

Conclusions:

  • The genome sequence of *S. aureus* strain 834 is now available.
  • This genomic data can facilitate research into *S. aureus* pathogenesis and resistance mechanisms.