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Risk Factors and Comorbidities in Young Indian Patients with Hypertension: REAL YOUNG (Hypertension) Study
Nagaraj Desai1, Govindan Unni2, Rajeev Agarwala3
1Namana Medical Center. Bangalore, Karnataka, India.
Insights
Hypertension is common in young Indian adults aged >35-45 years, often accompanied by diabetes and dyslipidemia. Risk factors include family history, sedentary habits, smoking, and alcohol use.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- Hypertension prevalence is increasing globally, including among younger populations.
- Understanding risk factors and comorbidities in young adults is crucial for early intervention.
Purpose of the Study:
- To analyze risk factors and comorbidities in young Indian adults diagnosed with hypertension.
- Identify demographic and lifestyle factors associated with hypertension in this age group.
Main Methods:
- Retrospective, multicentric real-world study of 15,006 patients aged 18-45 years in India.
- Data extracted from medical records included demographics, medical/family history, lifestyle factors.
- Descriptive and comparative statistical analyses were performed.
Main Results:
- Hypertension prevalent in >35-45 years age group (65.7%); 63.6% were men.
- Common comorbidities: diabetes mellitus (42.4%) and dyslipidemia (7.8%).
- Sedentary lifestyle (over 50%), smoking (47.3%), alcohol consumption (35.6%), and family history (56.7%) were significant.
Conclusions:
- Hypertension in young Indian adults is associated with older age within the young demographic, diabetes, and dyslipidemia.
- Family history, sedentary lifestyle, smoking, alcohol, and BMI are contributing factors.
Purpose:
To analyze the risk factors and comorbidities among the young Indian adults with hypertension.
Patients And Methods:
This was a retrospective, multicentric real-world study which included patients diagnosed with and receiving treatment for hypertension. Data were collected from the medical records of clinics/hospitals across 623 study sites in India. Patients of either sex and aged 18-45 years were included. Demographic details (age, sex, anthropometric measurement), medical and family history, sedentary lifestyle, smoking status and alcohol consumption data were extracted. Descriptive and comparative analysis (Mann-Whitney U and chi-squared test) was done.
Results:
Out of 15,006 young patients diagnosed with hypertension (men=63.6%), 65.7% belonged to the age group of >35-45 years. The median body mass index was 27.0 kg/m2. Patients diagnosed with only hypertension were 29.1% while other predominant comorbidities with hypertension were diabetes mellitus (42.4%) and dyslipidemia (7.8%). Hypertension with diabetes mellitus were prevalent in the age group of >35-45 years (43.8%). More than half of the patients with hypertension (n=7656) had a sedentary lifestyle. Overall, 35.6%, 47.3%, and 56.7% of the patients were alcoholic, smokers (present and former), and had a family history of hypertension, respectively.
Conclusion:
The results showed that among the young population, hypertension was common in the age group of >35-45 years and diabetes mellitus and dyslipidemia were common comorbidities. Family history, sedentary lifestyle, smoking, alcohol consumption, and body mass index may also contribute to hypertension.
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