Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comparison of fast and slow CO2 insufflation on hemodynamic parameters in elective laparoscopic cholecystectomy.

Journal of minimal access surgery·2026

Same author

AI may be systematically adversarial to adversarial cooperation.

Journal of medical ethics·2025

Same author

Examination of speech processing in noise reveals cognitive deficits in early Huntington's disease.

Cortex; a journal devoted to the study of the nervous system and behavior·2025

Same author

Change in liver fat content in patients following pancreatic resections.

Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology·2025

Same author

Temporal response patterns of Layer 4 rat barrel cortex neurons across various naturalistic whisker motions.

PloS one·2024

Same author

Role of Pancreatic Attenuation Index in Assessing Pancreatic Fat Content and Postpancreatectomy Outcomes.

The Indian journal of radiology & imaging·2024

Search research articles

Related Experiment Video

Updated: Nov 15, 2025

A System for Tracking the Dynamics of Social Preference Behavior in Small Rodents

A System for Tracking the Dynamics of Social Preference Behavior in Small Rodents

Published on: November 21, 2019

Sensing and processing whisker deflections in rodents.

Thomas F Burns¹, Ramesh Rajan¹

¹Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.

|March 5, 2021

Summary

This summary is machine-generated.

New evidence challenges the classical model of whisker sensation processing. This review explores the neurophysiology of whisker deflections, highlighting exceptions that complicate sensory and cortical processing.

Keywords:

Sensory processing Barrel cortex Cortical column Inhibition Microcircuits Sensory pathway Septa Somatopy Thalamocortical pathway Whisker

More Related Videos

Flat-floored Air-lifted Platform: A New Method for Combining Behavior with Microscopy or Electrophysiology on Awake Freely Moving Rodents

Flat-floored Air-lifted Platform: A New Method for Combining Behavior with Microscopy or Electrophysiology on Awake Freely Moving Rodents

Published on: June 29, 2014

Whisker-signaled Eyeblink Classical Conditioning in Head-fixed Mice

Whisker-signaled Eyeblink Classical Conditioning in Head-fixed Mice

Published on: March 30, 2016

Related Experiment Videos

Last Updated: Nov 15, 2025

A System for Tracking the Dynamics of Social Preference Behavior in Small Rodents

A System for Tracking the Dynamics of Social Preference Behavior in Small Rodents

Published on: November 21, 2019

Flat-floored Air-lifted Platform: A New Method for Combining Behavior with Microscopy or Electrophysiology on Awake Freely Moving Rodents

Flat-floored Air-lifted Platform: A New Method for Combining Behavior with Microscopy or Electrophysiology on Awake Freely Moving Rodents

Published on: June 29, 2014

Whisker-signaled Eyeblink Classical Conditioning in Head-fixed Mice

Whisker-signaled Eyeblink Classical Conditioning in Head-fixed Mice

Published on: March 30, 2016

Area of Science:

Neuroscience
Sensory processing
Cortical circuits

Background:

The classical model describes sensory information flow from the barrel cortex layer IV upwards for processing and downwards for output.
This model is increasingly challenged by emerging neurophysiological evidence.

Purpose of the Study:

To review the neurophysiology of whisker deflection sensing and processing.
To emphasize general principles and highlight exceptions in the sensory pathway.
To identify research gaps for future investigation.

Main Methods:

Literature review of neurophysiological studies on whisker sensation.
Analysis of sensory information processing from whiskers to barrel cortex.
Synthesis of classical principles and recent findings.

Main Results:

Many processing principles align with the classical view of whisker sensation.
A growing number of exceptions to classical principles complicate the sensory system.
Exceptions necessitate careful interpretation of experimental results.

Conclusions:

The classical view of whisker processing requires revision due to new evidence.
Understanding exceptions is crucial for accurate interpretation of sensory data.
Further research is needed to fully elucidate whisker sensation and cortical processing.