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Updated: Nov 15, 2025
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Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
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Perioperative circulatory support for lung transplantation
Akihiro Ohsumi1, Hiroshi Date2
1Department of Thoracic Surgery, Kyoto University Hospital, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan. akohsumi@kuhp.kyoto-u.ac.jp.
General Thoracic and Cardiovascular Surgery
|March 5, 2021
Summary
Extracorporeal membrane oxygenation (ECMO) is now preferred over cardiopulmonary bypass (CPB) for lung transplantation support. ECMO use may reduce complications and improve short-term outcomes, but more research is needed.
Area of Science:
- Cardiovascular Surgery
- Pulmonary Medicine
- Transplantation Medicine
Background:
- Extracorporeal membrane oxygenation (ECMO) is increasingly utilized for circulatory support in lung transplantation.
- Historically, cardiopulmonary bypass (CPB) was the standard for this procedure.
Purpose of the Study:
- To review and compare the use of ECMO versus CPB in lung transplantation.
- To analyze the impact of ECMO on patient outcomes during and after lung transplantation.
Main Methods:
- Systematic literature search of PubMed (Medline) from 2000-2020.
- Keywords included: lung transplantation, ECMO, and CPB.
- Inclusion of English-language reports.
Main Results:
- Intraoperative ECMO use is linked to reduced blood product transfusion, shorter mechanical ventilation, and decreased hospital stay.
- Preoperative ECMO as a bridge to lung transplantation shows promising outcomes for critically ill patients.
Conclusions:
- ECMO appears to decrease postoperative complications and enhance short-term outcomes compared to CPB during lung transplantation.
- Further large-scale randomized controlled trials are necessary to confirm these findings.
- Preoperative ECMO shows potential benefits, requiring additional data from experienced transplant centers.
