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Chemical modification of steffimycin B

P F Wiley¹, D W Elrod, D E Harper

¹Research Laboratories, Upjohn Company, Kalamazoo, Michigan 49001.

The Journal of Antibiotics

|March 1, 1988

Abstract:

Fifteen 3-substituted analogues of steffimycin B (1) have been synthesized and their activity against P388 murine leukemia has been determined. Three of these were substantially more active than the parent compound.

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