Related Experiment Video

Updated: Nov 15, 2025

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer
07:59

Author Spotlight: Advancements in Molecular Biomarker Testing for Non-Squamous Non-Small Cell Lung Cancer

Published on: September 8, 2023

1.4K

NCCN Guidelines Insights: Non-Small Cell Lung Cancer, Version 2.2021

David S Ettinger1, Douglas E Wood2, Dara L Aisner3

  • 11The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Journal of the National Comprehensive Cancer Network : JNCCN
|March 5, 2021
PubMed

Insights

Recent updates to Non-Small Cell Lung Cancer (NSCLC) management guidelines focus on new targeted therapies and immunotherapies. These NCCN Guidelines Insights highlight key biomarker advancements impacting treatment decisions for NSCLC patients.

Area of Science:

  • Oncology
  • Clinical Practice Guidelines

Background:

  • Non-Small Cell Lung Cancer (NSCLC) management requires up-to-date clinical guidance.
  • The National Comprehensive Cancer Network (NCCN) provides comprehensive guidelines for cancer care.

Purpose of the Study:

  • To summarize recent NCCN Guidelines updates for Non-Small Cell Lung Cancer (NSCLC).
  • To focus on advancements in targeted therapies, immunotherapies, and associated biomarkers.

Main Methods:

  • Review of the latest NCCN Clinical Practice Guidelines for NSCLC.
  • Analysis of updates concerning targeted agents and immunotherapeutic strategies.
  • Identification of key biomarker-driven treatment recommendations.

Main Results:

  • Recent NCCN Guidelines incorporate novel targeted therapies based on specific molecular alterations.
  • Immunotherapy recommendations have been refined, particularly in relation to predictive biomarkers.
  • Updates address the integration of these therapies across different stages of NSCLC.

Conclusions:

  • The latest NCCN Guidelines provide crucial updates for optimizing NSCLC treatment.
  • Biomarker testing is essential for guiding the selection of targeted therapies and immunotherapies.
  • These advancements aim to improve outcomes for patients with Non-Small Cell Lung Cancer.

More Related Videos

Semi-automatic PD-L1 Characterization and Enumeration of Circulating Tumor Cells from Non-small Cell Lung Cancer Patients by Immunofluorescence10:29

Semi-automatic PD-L1 Characterization and Enumeration of Circulating Tumor Cells from Non-small Cell Lung Cancer Patients by Immunofluorescence

Published on: August 14, 2019

10.8K
Using 22C3 Anti-PD-L1 Antibody Concentrate on Biopsy and Cytology Samples from Non-small Cell Lung Cancer Patients07:43

Using 22C3 Anti-PD-L1 Antibody Concentrate on Biopsy and Cytology Samples from Non-small Cell Lung Cancer Patients

Published on: September 25, 2018

10.8K

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.1K
Standards of Care II01:19

Standards of Care II

Nurses bear specific legal responsibilities under several federal statutes, including:
882
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.5K
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
9.0K
Standards of Care I01:22

Standards of Care I

Federal statutes profoundly impact nursing practice, providing critical guidelines to ensure patient care is equitable, accessible, and of the highest quality. The following laws address distinct aspects of healthcare provision and patient rights:
911
Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

Nursing Interventions II: Selecting and Classifying the Nursing Interventions

Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
2.8K