Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Immunological Memory01:23

Immunological Memory

14.3K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
14.3K
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

1.5K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
1.5K
Development of Immunocompetence01:22

Development of Immunocompetence

578
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
578
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

1.6K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.6K
Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

6.0K
Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
6.0K
Active versus Passive Immunity01:31

Active versus Passive Immunity

9.3K
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
9.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antigenemia and oral lesions in paracoccidioidomycosis: is there a correlation?

Journal of applied oral science : revista FOB·2026
Same author

An improved high-performance liquid chromatography (HPLC) method for detection of variations in the hydroxyproline content of tissue homogenates from <i>Paracoccidioides brasiliensis</i>-infected mice.

The journal of venomous animals and toxins including tropical diseases·2024
Same author

Low-level LASER therapy accelerates fungal lesions cicatrization by increasing the production of Th1 and Th2 cytokines.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2024
See all related articles

Related Experiment Video

Updated: Nov 15, 2025

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
06:32

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

10.8K

Paracoccidioidomycosis Protective Immunity.

Eva Burger1

  • 1Department of Microbiology and Immunology, Universidade Federal de Alfenas, Alfenas 37130-001, Brazil.

Journal of Fungi (Basel, Switzerland)
|March 6, 2021
PubMed
Summary

Protective immunity against Paracoccidioides involves innate and acquired immune responses. Key components include neutrophils, natural killer cells, monocytes, cytokines, complement, and specific antibodies, all crucial for fungal clearance.

Keywords:
acquired immunityinnate immunityparacoccidioidomycosis

More Related Videos

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
09:57

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens

Published on: February 14, 2011

12.2K
Author Spotlight: Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis
06:57

Author Spotlight: Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Published on: May 12, 2023

2.7K

Related Experiment Videos

Last Updated: Nov 15, 2025

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
06:32

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

10.8K
Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
09:57

Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens

Published on: February 14, 2011

12.2K
Author Spotlight: Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis
06:57

Author Spotlight: Adjuvant Activity of Mycobacterium paratuberculosis in Enhancing the Immunogenicity of Autoantigens During Experimental Autoimmune Encephalomyelitis

Published on: May 12, 2023

2.7K

Area of Science:

  • Immunology
  • Mycology
  • Infectious Diseases

Background:

  • Paracoccidioides infection triggers a complex immune response.
  • Innate and adaptive immunity are essential for controlling Paracoccidioides.

Purpose of the Study:

  • To present the role of innate immunity components in paracoccidioidomycosis.
  • To discuss the controversial role of humoral immunity in Paracoccidioides infection.
  • To detail cellular immunity mechanisms against Paracoccidioides.

Main Methods:

  • Review of innate immune components (neutrophils, NK cells, monocytes, cytokines, complement).
  • Discussion of invariant receptors (Toll-like receptors, Dectins) in pathogen recognition.
  • Analysis of humoral immunity (antibodies) and cellular immunity (macrophages, T lymphocytes, cytokines).

Main Results:

  • Innate immunity relies on phagocytes, NK cells, monocytes, cytokines, and complement.
  • Invariant receptors detect fungal patterns, activating acquired immunity.
  • Cellular immunity involves activated macrophages, cytotoxic T lymphocytes, and T helper cell cytokines.

Conclusions:

  • Protective immunity against Paracoccidioides is a stepwise activation of cellular and soluble components.
  • Both innate and acquired immune mechanisms are vital for controlling Paracoccidioides.
  • The study clarifies the multifaceted immune defense against Paracoccidioides fungal infections.